HomeBiomarkersLiver & Kidney FunctioneGFR (Estimated Glomerular Filtration Rate)
Nutrients & Organ Health

eGFR (Estimated Glomerular Filtration Rate)

The clinical standard for kidney function — how efficiently your kidneys filter blood.

Optimal target> 90 mL/min/1.73m² (stage 1 CKD 60–89, stage 2 < 60)

What it measures

eGFR estimates how much blood your kidneys filter per minute, normalized to body surface area. It is calculated from serum creatinine, age, sex, and body size. eGFR is the clinical standard for detecting and staging chronic kidney disease.

Because eGFR accounts for individual factors that affect creatinine, it is more meaningful than creatinine alone for comparing kidney function across people and over time.

Why it matters

  • The clinical standard for detecting chronic kidney disease early.
  • Accounts for age, sex, and body size — more meaningful than creatinine alone.
  • Declining eGFR trends warrant prompt nephrology follow-up.
  • Essential baseline for anyone on nephrotoxic medications or high-protein diets.

What affects your levels

Kidney health and filtration capacity
Blood pressure and cardiovascular health
Diabetes and metabolic health
Certain medications (NSAIDs, some antibiotics)
Hydration status

How VitalDrop tracks it

  • Monthly eGFR trends catch gradual filtration decline long before annual physicals.
  • Paired with creatinine for a complete kidney function picture.
  • Useful baseline before starting new supplements or medications.
  • Physician review identifies results needing nephrology follow-up.

Related biomarkers

Frequently asked questions

An eGFR above 90 is generally considered normal. Values between 60–89 indicate mildly decreased function (stage 2 CKD if there are other signs of kidney damage), and below 60 indicates chronic kidney disease. The trend matters most — a declining eGFR warrants follow-up even if still above 60.

References & sources

01.
KDIGO Clinical Practice Guideline for Chronic Kidney Disease. Kidney Disease: Improving Global Outcomes, 2024.Source
02.
eGFR and Chronic Kidney Disease Detection. JAMA, 2021.
Medically reviewed by
DH
Reviewed by Dr. Hassan Nasser
Medical Director — www.detroitfacemd.com

Board-certified facial plastic & reconstructive surgeon; clinical reviewer for VitalDrop laboratory insights. Verified at www.detroitfacemd.com

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Medical disclaimer: This content is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. VitalDrop provides laboratory test results and educational insights for wellness tracking. Always consult a qualified healthcare provider regarding abnormal or concerning results. Results and AI-assisted summaries are not a medical diagnosis.